Trials & Filings

AbbVie Regimen Wallops Hep C

Sustained virologic response in 96% of patients

By: Gil Roth

President, Pharma & Biopharma Outsourcing Association

AbbVie has posted Phase III results for the investigational three direct-acting-antiviral (3D) regimen plus ribavirin in patients with chronic, genotype 1 (GT1) hepatitis C virus (HCV) infection. In the 394-patient study, 96% of patients who previously failed pegylated interferon and ribavirin treatment, including approximately 49% who were prior null responders, achieved sustained virologic response at 12 weeks (SVR12) with the regimen. The majority of patients were GT1a, considered a difficult...

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